The two factors (a peptide and a phospholipid) combine to create the perfect signalling mechanism to produce all the components of a tendon growth plate (the unique mechanism by which tendons grow and repair).
- With high SNZRpl concentrations tendon cells divide and create new cells.
- As these cells mature the high SNZRpl concentration elicits collagen production and extrusion into highly organized fibers.
- As the collagen fibers accumulate between the cells the local SNZRpl concentration decreases and the cells become the dormant cells found in adult tendon.
However, these dormant cells remain highly sensitive to SNZRpl concentrations and tendon remodeling and repair can be produced simply by the raising the concentration of SNZRpl in the local cellular environment.
